The role of gut microbiota in metabolic regulation

被引：2
|
作者：
Kravchuk, Ekaterina N. [1 ]
Neimark, Alexander E. [1 ]
Grineva, Elena N. [1 ]
Galagudza, Mikhail M. [1 ]
机构：
[1] Almazov North West Med Res Ctr, 2 Akkuratova Str, St Petersburg 197341, Russia
来源：
DIABETES MELLITUS | 2016年 / 19卷 / 04期
关键词：
intestinal microbiota; obesity; metabolic syndrome; short-chain fatty acid; bile acid;
D O I：
10.14341/DM7704
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Obesity and metabolic syndrome are among the major problems of modern society. The increase in obesity is associated with a corresponding increase in type 2 diabetes, cardiovascular disease and cancer. A huge amount of scientific research has been devoted to the development of methods to reduce obesity and its complications. In recent years, attention has shifted towards studying the intestinal microbiota not only as a possible component of the pathological process but also as a target of therapeutic intervention. Recent evidence, primarily from investigations in animal models, suggests that the intestinal microbiota affects nutrient acquisition and energy regulation. This review will discuss the role of the intestinal microbiota in metabolic processes as well as the latest developments on the improvement of disturbances specific to obesity and metabolic syndrome.
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页码：280 / 285
页数：6
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