IN-VITRO ADHESION AND INVASION OF SALMONELLA-ENTERICA SEROVAR HAVANA

被引:2
|
作者
JAFARI, A
BOUZARI, S
FARHOUDIMOGHADDAM, AA
PARSI, M
SHOKOUHI, F
机构
[1] Molecular Biology Unit, Pasteur Institute of Iran, Tehran 13164, Pasteur Avenue
关键词
SALMONELLA; HAVANA; BACTERIAL ADHESION; CELL INVASION;
D O I
10.1006/mpat.1994.1006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A total of 132 isolates of the Havana serovar of Salmonela enterica were studied for their adhesion to and invasion of Hela cells in the presence of D-mannose. A total of 124 (93.9%) isolates were adherent, and 51% of these were invasive. of these 124 strains 82 (66%) adhered to HeLa cells with a pattern typical for enteroaggregative (EAgg) Escherichia coli whereas the remaining 34% adhered in a non-aggregative (non-EAgg) pattern. of the 82 strains showing the EAgg pattern 60% were invasive whereas only 33% of the 49 non-EAgg isolates invaded HeLa cells (P <0.01). The action of mannose-sensitive type 1 pili was inhibited by the addition of D-mannose. Therefore we conclude that type 1 pili are not important in adhesion and invasion of Havana. © 1994 Academic Press.
引用
收藏
页码:65 / 70
页数:6
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