THE DIAGNOSTIC POTENTIAL OF FETAL RENAL BIOPSY

被引:7
|
作者
GRECO, P
LOVERRO, G
CARUSO, G
CLEMENTE, R
SELVAGGI, L
机构
[1] UNIV BARI,CATTEDRA PATOL OSTET & GINECOL R,I-70124 BARI,ITALY
[2] UNIV BARI,IST ANAT PATOL,CATTEDRA PATOL CARDIOVASC,I-70124 BARI,ITALY
关键词
RENAL ABNORMALITY; PRENATAL TISSUE BIOPSY;
D O I
10.1002/pd.1970130703
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The feasibility of fetal renal biopsy has been investigated in order to assess the diagnostic value of the histological specimen. Two fetuses with a severe bilateral renal abnormality (multicystic dysplastic kidney, Meckel-Gruber syndrome with polycystic kidney) and one fetus with Down syndrome (no detectable structural anomaly) were sampled. Histological findings in the biopsy specimens of cases 1 and 2 were diagnostic of an early obstructive renal disease. In case 3, the findings were consistent with normal development for gestational age of the kidney. Fetal renal biopsy is technically feasible; histological examination of the samples showed a good correlation with postnatal findings. Further studies of its diagnostic value are required.
引用
收藏
页码:551 / 556
页数:6
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