INTERIM USE OF JARVIK-7 AND NOVACOR ARTIFICIAL-HEART - BLOOD RHEOLOGY AND TRANSIENT ISCHEMIC ATTACKS (TIAS)

被引：0

作者：

HUNG, TC ^{[1
]}

BUTTER, DB ^{[1
]}

YIE, CL ^{[1
]}

SUN, Z ^{[1
]}

BOROVETZ, HS ^{[1
]}

KORMOS, RL ^{[1
]}

GRIFFITH, BP ^{[1
]}

HARDESTY, RL ^{[1
]}

机构：

[1] UNIV PITTSBURGH,SCH MED,DEPT SURG,PITTSBURGH,PA 15261

来源：

BIORHEOLOGY | 1991年 / 28卷 / 1-2期

关键词：

BLOOD RHEOLOGY; ARTIFICIAL HEART; BLOOD VISCOSITY; ERYTHROCYTE RIGIDITY; PLATELET AGGREGATION; TRANSIENT ISCHEMIC ATTACK;

D O I：

暂无

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The rheological properties of blood were studied in patients supported by both the Jarvik-7 total artificial heart (TAH) and Novacor left ventricular assist device (LVAD) as a bridge to cardiac transplantation. Both groups of patients had abnormalities in blood rheology which differed according to the type of device implanted as well as on the clinical state of the patient. The rheology of individual patients correlated well with their clinical status and outcome, with incidences of TIA's and/or stroke being accompanied by marked increases in relative blood viscosity, erythrocyte rigidity, fibrinogen concentration and platelet aggregation in varying combination. Observed abnormalities in blood rheology were also crucial to thrombus formation on artificial heart valves as well. Our results show that the therapeutic management of rheological parameters should prove to be a unique and clinically rewarding approach to these patients.

引用

页码：9 / 25

页数：17

共 22 条

[21] ACCURACY OF JARVIK-7 TOTAL ARTIFICIAL-HEART CARDIAC OUTPUTS DETERMINED BY THE CARDIAC-OUTPUT MONITORING AND DIAGNOSTIC UNIT
GOLDENBERG, IF
PEDERSEN, W
EMERY, RW
JOYCE, LD
MADISON, JD
JOHNSON, KE
SIEBOLD, CM
JORGENSEN, C
VONRUEDEN, TJ
PRITZKER, MR
VANTASSEL, RA
GOBEL, FL
CLINICAL RESEARCH, 1988, 36 (06): : A819 - A819
[22] LIVER AND KIDNEY-FUNCTION IN PATIENTS UNDERGOING MECHANICAL CIRCULATORY SUPPORT WITH JARVIK-7 ARTIFICIAL-HEART AS A BRIDGE TO TRANSPLANTATION
KAWAGUCHI, AT
GANDJBAHCH, I
PAVIE, A
MUNERETTO, C
SOLIS, E
LEGER, P
BORS, V
SZEFNER, J
VAISSIER, E
LEVASSEUR, JP
CABROL, A
CABROL, C
JOURNAL OF HEART TRANSPLANTATION, 1990, 9 (06): : 631 - 637

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