CHARACTERIZATION OF PERIPHERAL-BLOOD LYMPHOCYTE SUBSETS IN PATIENTS WITH BAKERS ASTHMA

被引：0
|
作者：
WITTEMANN, B
SOHMEN, R
ROSENAU, C
RADANT, S
GRIESHABER, R
机构：
来源：
ALLERGOLOGIE | 1994年 / 17卷 / 04期
关键词：
BAKERS ASTHMA; PERIPHERAL BLOOD LYMPHOCYTE SUBSETS; FLOW CYTOMETRY; T-CELL ACTIVATION;
D O I：
暂无
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Differences in peripheral-blood lymphocyte subsets and activation markers were detected in patients with bakers' asthma compared to normal controls. Most asthmatic bakers were characterized by increased numbers of CD4+/HLA-DR+ T cells, by CD8+/HLA-DR+ T cells, by CD4-/CD25+ cells as well as CD19+/CD23+ B cells. Furthermore asthmatic bakers showed elevated serum levels of soluble IL-2 receptor (sCD25) and soluble low-affinity Fc IgE receptor. These differences in the distribution and activation state of peripheral-blood lymphocyte suggest an important role of T cells in the pathogenesis of bakers' asthma.
引用
收藏
页码：166 / 168
页数：3
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