Integrins are heterodimeric plasma membrane glycoproteins involved in cell-matrix and cell-cell interactions. The present communication reviews the distribution of several of the currently known integrin subunits in the corneal epithelium. The corneal epithelium contains the following integrin heterodimers: alpha-2-beta-1, alpha-3-beta-1, and alpha-6-beta-4. The expression of alpha(v) with an unknown beta-subunit is also recognized, whereas the expression of alpha-4 and alpha-5 subunits remains controversial. Some of the changes occurring in the distribution of integrins in response to wounding will also be discussed.
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Univ Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USA
Jilin Univ, Hosp 2, Changchun, Jilin Province, Peoples R ChinaUniv Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USA
Lu, Huayi
Lu, Qingxian
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Univ Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USAUniv Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USA
Lu, Qingxian
Zheng, Yajuan
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Jilin Univ, Hosp 2, Changchun, Jilin Province, Peoples R ChinaUniv Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USA
Zheng, Yajuan
Li, Qiutang
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Univ Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USAUniv Louisville, Dept Ophthalmol & Visual Sci, Sch Med, James Graham Brown Canc Ctr, Louisville, KY 40292 USA