SYSTEMIC RESISTANCE TO METHOTREXATE IN TRANSGENIC MICE CARRYING A MUTANT DIHYDROFOLATE-REDUCTASE GENE

被引：32
|
作者：
ISOLA, LM
GORDON, JW
机构：
[1] CUNY MT SINAI SCH MED,DEPT OBSTET GYNECOL & REPROD SCI,1 GUSTAVE L LEVY PL,NEW YORK,NY 10029
[2] CUNY MT SINAI SCH MED,DEPT BIOCHEM,NEW YORK,NY 10029
[3] CUNY MT SINAI SCH MED,POLLY ANNENBERG LEVEE HEMATOL CTR,DEPT MED,NEW YORK,NY 10029
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1986年 / 83卷 / 24期
关键词：
D O I：
10.1073/pnas.83.24.9621
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：9621 / 9625
页数：5
相关论文
共 50 条
  • [21] SELECTIVE KILLING OF METHOTREXATE-RESISTANT CELLS CARRYING AMPLIFIED DIHYDROFOLATE-REDUCTASE GENES
    URLAUB, G
    LANDZBERG, M
    CHASIN, LA
    CANCER RESEARCH, 1981, 41 (05) : 1594 - 1601
  • [22] REACTIVATION OF DIHYDROFOLATE-REDUCTASE INHIBITED BY METHOTREXATE OR AMINOPTERIN
    JACKSON, RC
    NIETHAMMER, D
    HART, LI
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1977, 182 (02) : 646 - 656
  • [23] METHOTREXATE RESISTANT HUMAN KB CELLS - SIZE HETEROGENEITY OF DIHYDROFOLATE-REDUCTASE RELATED RNAS AND EFFECT OF METHOTREXATE ON DIHYDROFOLATE-REDUCTASE ACTIVITY
    DOMIN, BA
    BASTOW, KF
    GRILL, SP
    CHENG, YC
    FEDERATION PROCEEDINGS, 1982, 41 (04) : 1052 - 1052
  • [24] METHOTREXATE METABOLISM IN MUTANT CHINESE-HAMSTER OVARY CELLS LACKING DIHYDROFOLATE-REDUCTASE
    JOANNON, P
    WHITEHEAD, VM
    ROSENBLATT, DS
    VUCHICH, MJ
    BEAULIEU, D
    BIOCHEMICAL PHARMACOLOGY, 1987, 36 (07) : 1091 - 1097
  • [25] Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene
    Budak-Alpdogan, T
    Alpdogan, O
    Banerjee, D
    Wang, E
    Moore, MAS
    Bertino, JR
    MOLECULAR THERAPY, 2004, 10 (03) : 574 - 584
  • [26] HUMAN DIHYDROFOLATE-REDUCTASE (DHFR) GENE AMPLIFICATION AFTER METHOTREXATE (MTX) TREATMENT
    HORNS, RC
    DOWER, WJ
    SCHIMKE, RT
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1983, 24 (MAR): : 280 - 280
  • [27] LYSINE AND ORNITHINE ANALOGS OF METHOTREXATE AS INHIBITORS OF DIHYDROFOLATE-REDUCTASE
    KEMPTON, RJ
    BLACK, AM
    ANSTEAD, GM
    KUMAR, AA
    BLANKENSHIP, DT
    FREISHEIM, JH
    JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (04) : 475 - 477
  • [28] FLUORESCENT ANALOGS OF METHOTREXATE - CHARACTERIZATION AND INTERACTION WITH DIHYDROFOLATE-REDUCTASE
    KUMAR, AA
    KEMPTON, RJ
    ANSTEAD, GM
    FREISHEIM, JH
    BIOCHEMISTRY, 1983, 22 (02) : 390 - 395
  • [29] BINDING OF METHOTREXATE TO DIHYDROFOLATE-REDUCTASE BY QUANTUM CHEMICAL CALCULATION
    RICHARDS, WG
    CUTHBERTSON, AF
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1984, (03) : 167 - 168
  • [30] KINETIC-PARAMETERS OF DIHYDROFOLATE-REDUCTASE INHIBITED BY METHOTREXATE
    CHA, S
    KIM, SYR
    KORNSTEIN, SG
    KANTOFF, PW
    KIM, KH
    FEDERATION PROCEEDINGS, 1980, 39 (06) : 2214 - 2214
12345