EARLY DUCTAL LESIONS OF PANCREATIC CARCINOGENESIS IN ANIMALS AND HUMANS

被引：0
|
作者：
KONISHI, Y [1 ]
MIZUMOTO, K [1 ]
KITAZAWA, S [1 ]
TSUJIUCHI, T [1 ]
TSUTSUMI, M [1 ]
KAMANO, T [1 ]
机构：
[1] JUNTENDO UNIV,SCH MED,DEPT SURG 1,BUNKYO KU,TOKYO 113,JAPAN
来源：
INTERNATIONAL JOURNAL OF PANCREATOLOGY | 1990年 / 7卷 / 1-3期
关键词：
HYPERPLASIA; INTRADUCTAL CARCINOMA; INVASIVE CARCINOMA; CEA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Two cases of human early pancreatic duct adenocarcinoma were presented, and ductal lesions observed histologically were compared to those induced in hamsters using a rapid-production model of pancreatic carcinoma. In human cases, direct histologic evidence was obtained to suggest that cancerous changes arose from duct epithelial cell hyperplasia, because lesions of hyperplasia and carcinoma coexisted in continuity. In hamster serial-killing studies, it was suggested that carcinoma developed through atypical ductal hyperplasia.
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页码：83 / 89
页数：7
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