GASTROINTESTINAL MANIFESTATIONS OF AMYLOIDOSIS

被引:34
|
作者
LEE, JG [1 ]
WILSON, JAP [1 ]
GOTTFRIED, MR [1 ]
机构
[1] DUKE UNIV,MED CTR,DEPT PATHOL,DURHAM,NC 27710
关键词
D O I
10.1097/00007611-199402000-00019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We reviewed gastrointestinal manifestations in 40 patients with amyloidosis. Gastrointestinal symptoms included anorexia, macroglossia, intestinal pseudo-obstruction, and altered bowel habits. Hepatomegaly was detected in eight patients, but none had clinically significant infiltrative liver disease. Mucosal friability and erosions were common endoscopic findings. Barium enema was noncontributory in the diagnosis of amyloidosis, since colonoscopy disclosed mucosal abnormalities in three of six patients with normal radiographic findings. Rectal biopsy had the highest diagnostic yield, followed by duodenal, gastric, and colonic biopsies.
引用
收藏
页码:243 / 247
页数:5
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