DITHIO AND THIONO ESTERS .55. SYNTHESIS OF N-PROTECTED, OPTICALLY-ACTIVE ALPHA-AMINO THIONO ESTERS

被引：0

作者：

BRUTSCHE, A ^{[1
]}

HARTKE, K ^{[1
]}

机构：

[1] UNIV MARBURG,INST PHARMAZEUT CHEM,MARBACHER WEG 6,W-3550 MARBURG,GERMANY

来源：

LIEBIGS ANNALEN DER CHEMIE | 1992年 / 09期

关键词：

THIONIC ESTERS; AMINO ACIDS; AMINO AMIDES; IMINIUM SALTS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The N-protected alpha-amino amides 1 are O-alkylated with trialkyloxonium tetrafluoroborates to form the iminium salts 2. Sulfhydrolysis of 2 yields the alpha-amino thiono esters 3. This reaction sequence allows the preparation of enantiomerically pure 3.

引用

页码：921 / 925

页数：5

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