GLUCURONIDATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE - HUMAN AND RAT ENZYME SPECIFICITY

被引：64
|
作者：
RESETAR, A
SPECTOR, T
机构：
[1] BURROUGHS WELLCOME CO, DIV EXPTL THERAPY, RES TRIANGLE PK, NC 27709 USA
[2] UNIV N CAROLINA, DEPT PHARMACOL, CHAPEL HILL, NC 27514 USA
来源：
BIOCHEMICAL PHARMACOLOGY | 1989年 / 38卷 / 09期
关键词：
D O I：
10.1016/0006-2952(89)90177-9
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：1389 / 1393
页数：5
相关论文
共 50 条
  • [21] INVITRO INHIBITION STUDIES OF THE GLUCURONIDATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE CATALYZED BY HUMAN LIVER UDP-GLUCURONOSYL TRANSFERASE
    MACLEOD, R
    EAGLING, VA
    SIM, SM
    BACK, DJ
    [J]. BIOCHEMICAL PHARMACOLOGY, 1992, 43 (02) : 382 - 386
  • [22] REDUCTION OF 3'-AZIDO-3'-DEOXYTHYMIDINE IN HUMAN LIVER-MICROSOMES
    CRETTON, EM
    PANZHOU, XR
    MAUREL, P
    SOMMADOSSI, JP
    [J]. BLOOD, 1993, 82 (10) : A414 - A414
  • [23] Comparison of the mechanism of toxicity of 3 '-azido-3 '-deoxythymidine and 3 '-fluoro-3 '-deoxythymidine in human lymphocytes
    Cox, S.
    Harmenberg, J.
    [J]. ANTIVIRAL CHEMISTRY & CHEMOTHERAPY, 1990, 1 (04): : 269 - 277
  • [24] 3'-Azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta
    Collier, AC
    Helliwell, RJA
    Keelan, JA
    Paxton, JW
    Mitchell, MD
    Tingle, MD
    [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 2003, 192 (02) : 164 - 173
  • [25] AN EFFICIENT SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT)
    CZERNECKI, S
    VALERY, JM
    [J]. SYNTHESIS-STUTTGART, 1991, (03): : 239 - 240
  • [26] GLUCURONIDATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE CATALYZED BY HUMAN LIVER UDP-GLUCURONOSYLTRANSFERASE - SIGNIFICANCE OF NUCLEOSIDE HYDROPHOBICITY AND INHIBITION BY XENOBIOTICS
    RESETAR, A
    MINICK, D
    SPECTOR, T
    [J]. BIOCHEMICAL PHARMACOLOGY, 1991, 42 (03) : 559 - 568
  • [27] A CONFORMATIONAL-ANALYSIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE
    SABIO, M
    TOPIOL, S
    [J]. JOURNAL OF COMPUTATIONAL CHEMISTRY, 1992, 13 (04) : 478 - 491
  • [28] The process for making 3′-azido-3′-deoxythymidine (AZT)
    Kulig-Adamiak, A
    Beldowicz, M
    Kaminski, J
    Lewicka, L
    Kakol, B
    Wisniewska, A
    Kazimierczuk, Z
    [J]. PRZEMYSL CHEMICZNY, 2004, 83 (11): : 553 - 558
  • [29] A SIMPLIFIED SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT)
    MANDAL, SB
    ACHARI, B
    [J]. JOURNAL OF CHEMICAL RESEARCH-S, 1993, (08): : 326 - 327
  • [30] GLUCURONIDATION OF 3'-AZIDO-3'-DEOXY-THYMIDINE (AZT) BY RAT AND HUMAN-LIVER MICROSOMES
    CRETTON, EM
    BEVAN, R
    SOMMADOSSI, JP
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1989, 45 (02) : 182 - 182
12345