Gdown1 Making a link between Mediator and RNA polymerase II elongation control

被引：6

作者：

Li, Tiandao ^{[1
]}

Price, David H. ^{[1
]}

机构：

[1] Univ Iowa, Dept Biochem, Iowa City, IA 52242 USA

来源：

TRANSCRIPTION-AUSTIN | 2012年 / 3卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Gdown1; POLR2M; P-TEFb; Mediator; NELF; DSIF; RNA polymerase II;

D O I：

10.4161/trns.20600

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Gdown1 is a substoichiometric RNA polymerase II subunit that modulates effects of both Mediator and elongation factors in vitro and is broadly distributed across the human genome. Here we assemble the existing information on Gdown1, provide additional bioinformatics analyses, and propose a working model for Gdown1 function.

引用

页码：177 / 180

页数：4

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