BIOCOMPATIBLE NONIONIC SURFACTANTS FOR BIOMEDICAL UTILIZATION - DOUBLE-TAILED HYDROCARBON AND OR FLUOROCARBON SYNTHETIC GLYCOLIPIDS

被引:9
|
作者
PUCCI, B [1 ]
GUEDJ, C [1 ]
PAVIA, AA [1 ]
机构
[1] FAC SCI AVIGNON,CHIM BIOORGAN LAB,33 RUE LOUIS PASTEUR,F-84000 AVIGNON,FRANCE
关键词
D O I
10.1016/S0960-894X(00)80276-0
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Two classes of double-tailed hydrocarbon and/or fluorocarbon glycolipids containing either a gluco- or a galactopyranose residue in their hydrophilic head have been synthesized. The first was obtained upon opening a maltono- or lactonolactone moiety by the amino group of glycine followed by condensation of the glycine carboxylic function with a double-chain primary amine. The second involves L-lysine in place of glycine. Formation of vesicular structures upon conventional treatment was confirmed by preliminary measurements.
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页码:1003 / 1006
页数:4
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