A-63162, A POTENT ORALLY ACTIVE INHIBITOR OF 5-LIPOXYGENASE (5-LO)

被引：0
|
作者：
CARTER, GW [1 ]
YOUNG, PR [1 ]
DYER, R [1 ]
ALBERT, DH [1 ]
BOUSKA, J [1 ]
BARLOW, J [1 ]
ROBERTS, E [1 ]
SONSALLA, J [1 ]
SUMMERS, J [1 ]
BROOKS, D [1 ]
机构：
[1] ABBOTT LABS, N CHICAGO, IL 60064 USA
来源：
FASEB JOURNAL | 1988年 / 2卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：A1263 / A1263
页数：1
相关论文
共 50 条
  • [1] INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH A-53612, A SELECTIVE AND ORALLY ACTIVE INHIBITOR OF 5-LIPOXYGENASE (5-LO)
    ALBERT, DH
    DYER, R
    YOUNG, PR
    BARLOW, J
    BORNEMEIER, D
    BOUSKA, J
    ROBERTS, E
    SONSALLA, J
    BROOKS, DW
    CARTER, GW
    FASEB JOURNAL, 1988, 2 (04): : A369 - A369
  • [2] CHARACTERIZATION OF CGS-8515 AS A SELECTIVE 5-LIPOXYGENASE (5-LO) INHIBITOR
    KU, EC
    RAYCHAUDHURI, A
    GHAI, G
    KIMBLE, EF
    LEE, WH
    COLOMBO, C
    DOTSON, R
    WHITE, D
    OGLESBY, TD
    WASLEY, JWF
    ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH, 1989, 19 : 86 - 89
  • [3] R-85355 - A POTENT, ORALLY ACTIVE 5-LIPOXYGENASE INHIBITOR
    BEETENS, JR
    BEERENS, D
    VANAMMEL, K
    SOMERS, Y
    LOOTS, W
    DECLERCK, F
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1991, 419 (01): : R3 - R3
  • [4] A-64077, A NEW POTENT ORALLY ACTIVE 5-LIPOXYGENASE INHIBITOR
    CARTER, GW
    YOUNG, PR
    ALBERT, DH
    BOUSKA, JB
    DYER, RD
    BELL, RL
    SUMMERS, JB
    BROOKS, DW
    GUNN, BP
    RUBIN, P
    KESTERSON, J
    LEUKOTRIENES AND PROSTANOIDS IN HEALTH AND DISEASE, 1989, 3 : 50 - 55
  • [5] Genes in the 5-lipoxygenase (5-LO) pathway : association with COPD
    Sims, A. -M.
    Damholt, A.
    Knutsson, M.
    Carlholm, M.
    Carlsson, L. -G.
    Lofdahl, C. -G.
    Postma, D.
    Semb, K. F.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181
  • [6] The 5-lipoxygenase (5-LO) cascade and atherosclerosis in mice and men
    Loetzer, K
    Graebner, R
    Kaiser, B
    John, N
    Moos, M
    Spanbroek, R
    Hildner, M
    Funke, H
    Habenicht, AJR
    CHEMISTRY AND PHYSICS OF LIPIDS, 2004, 130 (01) : 21 - 22
  • [7] 5-lipoxygenase (5-LO) is involved in Kupffer cell survival
    Titos, E
    Claria, J
    Planaguma, A
    Lopez-Parra, M
    Villamor, N
    Jimenez, W
    Arroyo, V
    Rivera, F
    Rodés, J
    JOURNAL OF HEPATOLOGY, 2002, 36 : 75 - 75
  • [8] The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model
    Jeffs, Alexander D.
    Boyd, Michael
    Larabee, Landon
    Shelton, Matthew
    Bassil, Alexander
    Taylor, Ross
    Berkoff, David
    JOURNAL OF EXPERIMENTAL ORTHOPAEDICS, 2023, 10 (01)
  • [9] The role of leukotriene inhibition using a 5-lipoxygenase (5-LO) inhibitor in a joint contracture model
    Alexander D. Jeffs
    Michael Boyd
    Landon Larabee
    Matthew Shelton
    Alexander Bassil
    Ross Taylor
    David Berkoff
    Journal of Experimental Orthopaedics, 10
  • [10] THE EFFECTS OF 5-LIPOXYGENASE (5-LO) INHIBITORS IN A MODEL OF ENDOTOXEMIA IN THE RAT
    YOUNG, PR
    RACH, W
    BARLOW, J
    SONSALLA, J
    ALBERT, DH
    SUMMERS, JB
    BROOKS, DW
    CARTER, GW
    FASEB JOURNAL, 1988, 2 (05): : A1264 - A1264
12345