THE HUMAN GENES FOR COMPLEMENT COMPONENT-6 (C6) AND COMPONENT-9 (C9) ARE CLOSELY LINKED ON CHROMOSOME-5

被引：9
|
作者：
ROGNE, S
MYKLEBOST, O
OLVING, JH
KYRKJEBO, HT
JONASSEN, R
OLAISEN, B
GEDDEDAHL, T
机构：
[1] NORWEGIAN RADIUM HOSP,INST CANC RES,DEPT TUMOR BIOL,N-0310 OSLO 3,NORWAY
[2] UNIV OSLO,RIKSHOSP,INST FORENS MED,N-0027 OSLO 1,NORWAY
[3] NORWEGIAN RADIUM HOSP,INST CANC RES,DEPT GENET,N-0310 OSLO 3,NORWAY
[4] UNIV TROMSO,N-9000 TROMSO,NORWAY
[5] REG HOSP CORK,POLAR INST MED GENET,N-9000 TROMSO,NORWAY
来源：
JOURNAL OF MEDICAL GENETICS | 1991年 / 28卷 / 09期
关键词：
D O I：
10.1136/jmg.28.9.587
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
We have used a cDNA probe for human complement component 9 (C9), which detects three DNA polymorphisms, to analyse the inheritance of C9 in families informative for C6 protein variants. We found that these genes are closely linked with a lod score of 9.28 at recombination fraction 0.00. There is no indication of allelic association.
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收藏
页码：587 / 590
页数：4
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