MUCOSAL IMMUNITY TO INFECTION WITH IMPLICATIONS FOR VACCINE DEVELOPMENT

被引:171
|
作者
STAATS, HF
JACKSON, RJ
MARINARO, M
TAKAHASHI, I
KIYONO, H
MCGHEE, JR
机构
[1] OSAKA UNIV,SUITA,OSAKA 565,JAPAN
[2] UNIV ALABAMA,DEPT MICROBIOL,BIRMINGHAM,AL 35294
关键词
D O I
10.1016/0952-7915(94)90144-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The induction of effective mucosal immunity that also provides systemic immunity is a considerable challenge. Over the past two years, efforts to develop novel mucosal vaccine delivery systems to induce mucosal immunity against bacterial and viral diseases, including HIV, have dramatically increased. Here we cite novel vaccines and delivery systems being used to establish effective mucosal immunity.
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页码:572 / 583
页数:12
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