ORAL IMMUNOTHERAPY WITH GRASS-POLLEN IN ENTEROSOLUBLE CAPSULES - A PROSPECTIVE-STUDY OF THE CLINICAL AND IMMUNOLOGICAL RESPONSE

被引：30

作者：

URBANEK, R

BURGELIN, KH

KAHLE, S

KUHN, W

WAHN, U

机构：

[1] RUHR UNIV BOCHUM,KINDERKLIN,W-4630 BOCHUM,GERMANY

[2] FREE UNIV BERLIN,KINDERKLIN,W-1000 BERLIN 33,GERMANY

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1990年 / 149卷 / 08期

关键词：

Enterosoluble capsules; Grass pollen allergy; Oral hyposensitization;

D O I：

10.1007/BF01957689

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

In a prospective study spanning 2 years, 60 patients with grass pollen allergy were treated with either a low dose oral, a high dose oral or a subcutaneous hyposensitization regime. No significant improvement was seen in the orally treated patients whereas those on the subcutaneous hyposensitization regime demonstrated a decreased specific cutaneous reactivity, a rise in specific IgG antibodies and a reduction in symptoms. This study suggests that oral hyposensitization, even with enterosoluble grass pollen capsules, is ineffective. © 1990 Springer-Verlag.

引用

页码：545 / 550

页数：6

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