EFFECTS OF 2 5-HT AGONISTS ON TRH-INDUCED TSH SECRETION IN RATS

被引:0
|
作者
TOIVONEN, M [1 ]
MANNISTO, PT [1 ]
机构
[1] UNIV HELSINKI,NEUROBIOL RES UNIT,HELSINKI,FINLAND
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暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Intraperitoneal injection of (+/-)-1-(2,5-dimethoxy-4-iodophenyl) -2-aminopropane (DOI), a 5-HT2 agonist, and subcutaneous (s.c.) injection of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT), a 5-HT1(A) agonist, had no effect on basal TSH secretion in male rats. However, TRH-induced TSH secretion was significantly inhibited by pretreatment with DOI, but not by 8-OH-DPAT.
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页码:257 / 261
页数:5
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