HALF-LIFE OF HUMAN PTH INVIVO - PEROPERATIVE STUDY IN THE TREATMENT OF PARATHYROID ADENOMAS

被引：0
|
作者：
WERYHA, G
KAMINSKY, P
DETALANCE, N
SCHJOT, B
DUQUENNE, M
MATHIEU, P
LECLERE, J
机构：
来源：
REVUE DE MEDECINE INTERNE | 1992年 / 13卷
关键词：
D O I：
10.1016/S0248-8663(05)80947-6
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Using a sensitive two-site immunoradiometric assay which detects intact PTH, we studied the kinetics of PTH secretion undergoing unilateral neck exploration and removal of a parathyroid adenoma. Analysis of the rate ot disappearance of PTH indicated a tri-eponential clearance pattern. The early phase had a half-life of 10,8 mn, the second phase had a half-life of 86 mn, the last phase had a half-life of 5 hours.
引用
收藏
页码：S360 / S360
页数：1
相关论文
共 50 条
  • [21] INVIVO HALF-LIFE OF RAT ATRIAL-NATRIURETIC-FACTOR (ANF)
    MURTHY, KK
    THIBAULT, G
    SCHIFFRIN, EL
    GARCIA, R
    CHARTIER, L
    GUTKOWSKA, J
    GENEST, J
    CANTIN
    FEDERATION PROCEEDINGS, 1986, 45 (04) : 1025 - 1025
  • [22] HALF-LIFE AND INVIVO RECOVERY OF HEATED FACTOR-VIII CONCENTRATES
    MORFINI, M
    MESSORI, A
    LONGO, G
    CINOTTI, S
    MATUCCI, M
    FERRINI, PR
    LANCET, 1986, 2 (8506): : 571 - 572
  • [23] HUMAN PARATHYROID TUMORS SECRETE COOH-TERMINAL FRAGMENTS OF PARATHYROID-HORMONE (PTH) INVIVO
    FLUECK, JA
    EDIS, AJ
    MCMAHON, JM
    ARNAUD, CD
    CLINICAL RESEARCH, 1975, 23 (04): : A498 - A498
  • [24] DISTRIBUTION AND HALF-LIFE OF 131I-LABELED PARATHYROID HORMONE IN RAT
    MELICK, RA
    AURBACH, GD
    POTTS, JT
    ENDOCRINOLOGY, 1965, 77 (01) : 198 - &
  • [25] Preclinical development of EXT608, an investigational parathyroid hormone derivative with extended half-life for the treatment of hypoparathyroidism
    Hall, Daniel B.
    Kostyla, Caroline H.
    Hales, Laura M.
    Soliman, Tarik M.
    JBMR PLUS, 2024, 8 (06)
  • [26] MEASUREMENT OF HALF-LIFE OF HUMAN-PLASMA FIBRINOGEN
    STEIN, TP
    LESKIW, MJ
    WALLACE, HW
    AMERICAN JOURNAL OF PHYSIOLOGY, 1978, 234 (05): : E504 - E510
  • [27] Proteome Half-Life Dynamics in Living Human Cells
    Eden, Eran
    Geva-Zatorsky, Naama
    Issaeva, Irina
    Cohen, Ariel
    Dekel, Erez
    Danon, Tamar
    Cohen, Lydia
    Mayo, Avi
    Alon, Uri
    SCIENCE, 2011, 331 (6018) : 764 - 768
  • [28] BIOLOGICAL HALF-LIFE OF TRICHLOROETHYLENE AND TETRACHLOROETHYLENE IN HUMAN SUBJECTS
    IKEDA, M
    IMAMURA, T
    INTERNATIONALES ARCHIV FUR ARBEITSMEDIZIN, 1973, 31 (03): : 209 - 224
  • [29] EFFECT OF PHENOBARBITAL TREATMENT ON RIFAMPICIN HALF-LIFE IN MAN
    ACOCELLA, G
    BONOLLO, L
    MARGAROL.P
    ACTA VITAMINOLOGICA ET ENZYMOLOGICA, 1972, 26 (3-4) : 129 - &
  • [30] Exploring the half-life of glyphosate in human urine samples
    Connolly, Alison
    Jones, Kate
    Basinas, Ioannis
    Galea, Karen S.
    Kenny, Laura
    McGowan, Padraic
    Coggins, Marie A.
    INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2019, 222 (02) : 205 - 210
12345