The impact of transcriptional cycling on gene regulation

被引：4
|
作者：
Carlberg, Carsten [1 ,2 ]
机构：
[1] Univ Luxembourg, Life Sci Res Unit, Luxembourg, Luxembourg
[2] Univ Eastern Finland, Dept Biosci, Kuopio, Finland
来源：
TRANSCRIPTION-AUSTIN | 2010年 / 1卷 / 01期
基金：
芬兰科学院;
关键词：
transcription; gene regulation; nuclear receptor; chromatin; stochastic modeling;
D O I：
10.4161/trns.1.1.11984
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Research of the past decade showed that transcriptional regulation could be a highly dynamic and cyclical process. Many transcription factors and their co-regulators cyclically associate with a periodicity of 30-75 min with regulatory chromatin regions resulting in dynamically changing chromatin marks and cyclical activities of RNA polymerase II in mRNA synthesis.
引用
收藏
页码：13 / 16
页数：4
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