THE ANNEXINS AND EXOCYTOSIS

被引：534
|
作者：
CREUTZ, CE
机构：
[1] Department of Pharmacology, University of Virginia, Charlottesville
来源：
SCIENCE | 1992年 / 258卷 / 5084期
关键词：
D O I：
10.1126/science.1439804
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The annexins are a group of homologous proteins that bind phospholipids in the presence of calcium. They may provide a major pathway for communication between cellular membranes and their cytoplasmic environment. Annexins have a characteristic "bivalent" activity in the sense that they can draw two membranes together when activated by calcium. This has led to the hypothesis that certain members of this protein family may initiate contact and fusion between a secretory vesicle membrane and the plasma membrane during the process of exocytosis.
引用
收藏
页码：924 / 931
页数：8
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