THE INSULIN-RECEPTOR ALPHA-SUBUNIT MEDIATES INSULIN BINDING AND THE BETA-SUBUNIT IS A PROTEIN-KINASE

被引：0
|
作者：
ROTH, RA
CASSELL, DJ
MESIROW, ML
机构：
[1] UNIV CALIF SAN FRANCISCO,SAN FRANCISCO,CA 94143
[2] MT ZION HOSP & MED CTR,SAN FRANCISCO,CA 94120
来源：
FEDERATION PROCEEDINGS | 1983年 / 42卷 / 07期
关键词：
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：1790 / 1790
页数：1
相关论文
共 50 条
  • [31] A CASCADE OF TYROSINE AUTOPHOSPHORYLATION IN THE BETA-SUBUNIT ACTIVATES THE PHOSPHOTRANSFERASE OF THE INSULIN-RECEPTOR
    WHITE, MF
    SHOELSON, SE
    KEUTMANN, H
    KAHN, CR
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1988, 263 (06) : 2969 - 2980
  • [32] TRANSMEMBRANE SIGNALING BY AN INSULIN-RECEPTOR LACKING A CYTOPLASMIC BETA-SUBUNIT DOMAIN
    SASAOKA, T
    LANGLOIS, WJ
    DIABETES, 1993, 42 : A82 - A82
  • [33] INFLUENCE OF INSULIN-RECEPTOR ALPHA-SUBUNIT PROTEOLYSIS ON HORMONE-RECEPTOR INTERACTIONS
    YUSTA, B
    SANCHEZCASAS, P
    BLAZQUEZ, E
    DIABETOLOGIA, 1992, 35 : A82 - A82
  • [34] AN EXTRACELLULAR DOMAIN OF THE BETA-SUBUNIT IS ESSENTIAL FOR PROCESSING, TRANSPORT AND KINASE-ACTIVITY OF INSULIN-RECEPTOR
    HARUTA, T
    SAWA, T
    TAKATA, Y
    IMAMURA, T
    TAKADA, Y
    MORIOKA, H
    YANG, GH
    KOBAYASHI, M
    BIOCHEMICAL JOURNAL, 1995, 305 : 599 - 604
  • [35] THE INSULIN-RECEPTOR IS AN INSULIN RESPONSIVE PROTEIN-KINASE
    VANOBBERGHEN, E
    BALLOTTI, R
    GAMMELTOFT, S
    ROSSI, B
    LEMARCHANDBRUSTEL, Y
    FEHLMANN, M
    KOWALSKI, A
    BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1985, 366 (09): : 862 - 862
  • [36] INSULIN STIMULATES PROTEOLYSIS OF THE ALPHA-SUBUNIT, BUT NOT THE BETA-SUBUNIT, OF ITS RECEPTOR AT THE CELL-SURFACE IN RAT-LIVER
    LIPSON, KE
    KOLHATKAR, AA
    DONNER, DB
    BIOCHEMICAL JOURNAL, 1989, 261 (02) : 333 - 340
  • [37] MUTATION OF THE HIGH CYSTEINE REGION OF THE HUMAN INSULIN-RECEPTOR ALPHA-SUBUNIT INCREASES INSULIN-RECEPTOR BINDING-AFFINITY AND TRANSMEMBRANE SIGNALING
    RAFAELOFF, R
    PATEL, R
    YIP, C
    GOLDFINE, ID
    HAWLEY, DM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1989, 264 (27) : 15900 - 15904
  • [38] THE GABAA/BENZODIAZEPINE RECEPTOR IS A HETEROTETRAMER OF HOMOLOGOUS ALPHA-SUBUNIT AND BETA-SUBUNIT
    MAMALAKI, C
    STEPHENSON, FA
    BARNARD, EA
    EMBO JOURNAL, 1987, 6 (03): : 561 - 565
  • [39] AN EXTRACELLULAR DISTRICT OF THE INSULIN-RECEPTOR BETA SUBUNIT WITH REGULATORY FUNCTION ON PROTEIN TYROSINE KINASE
    GHERZI, R
    DEPIRRO, R
    ANDRAGHETTI, G
    SESTI, G
    MONTEMURRO, A
    CORDERA, R
    DIABETOLOGIA, 1988, 31 (07) : A493 - A493
  • [40] PROTEIN-KINASE-C AND INSULIN-RECEPTOR BETA-SUBUNIT SERINE PHOSPHORYLATION IN CULTURED FETAL-RAT HEPATOCYTES
    ZACHAYUS, JL
    CHERQUI, G
    PLAS, C
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1994, 105 (01) : 11 - 20
12345