Bile acids from a Marine Sponge-Associated Fungus Penicillium sp

被引:2
|
作者
Pil, Gam Bang [1 ,2 ]
Won, Ho Shik [2 ]
Shin, Hee Jae [1 ]
机构
[1] Korea Inst Ocean Sci & Technol, Marine Nat Prod Lab, Ansan, South Korea
[2] Hanyang Univ, Dept Chem & Appl Chem, Seoul, South Korea
来源
关键词
Marine natural products; cholic acid; glycocholic acid; bile acids; marine fungus; Penicillium sp;
D O I
10.6564/JKMRS.2016.20.2.041
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Chemical investigation of a marine-derived fungus, Penicillium sp. 108YD020, resulted in the discovery of six bile acid derivatives, glycocholic acid (1), glycocholic acid methyl ester (2), cholic acid (3), glycochenodeoxycholic acid (4), glycodeoxycholic acid methyl ester (5), and cholic acid methyl ester (6). The structures of six bile acid derivatives 1-6 were determined by the detailed analysis of 1D, 2D NMR and LC-MS data, along with chemical methods and literature data analysis.
引用
收藏
页码:41 / 45
页数:5
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