SYNTHESIS AND ABSOLUTE-CONFIGURATION OF (+)-HAPALINDOLE-Q

被引：75

作者：

VAILLANCOURT, V ^{[1
]}

ALBIZATI, KF ^{[1
]}

机构：

[1] WAYNE STATE UNIV,DEPT CHEM,DETROIT,MI 48202

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1993年 / 115卷 / 09期

关键词：

D O I：

10.1021/ja00062a013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The versatility of brominated camphor derivatives as six-membered-ring chiral building blocks in the synthesis of compounds of mixed biogenesis has been demonstrated in an eight-step synthesis of (+)-hapalindole Q from (+)-(1R)-9-bromocamphor in an overall 8% yield which confirms the absolute stereochemistry to be 10R, 11R, 12R, 15R.

引用

页码：3499 / 3502

页数：4

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