Selenoprotein P in colitis-associated carcinoma

被引：7

作者：

Short, Sarah P. ^{[1
,2
,3
]}

Whitten-Barrett, Caitlyn ^{[1
,2
,3
]}

Williams, Christopher S. ^{[1
,2
,3
,4
]}

机构：

[1] Vanderbilt Univ, Dept Med, Div Gastroenterol, 221 Kirkland Hall, Nashville, TN 37235 USA

[2] Vanderbilt Univ, Dept Canc Biol, 221 Kirkland Hall, Nashville, TN 37235 USA

[3] Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA

[4] Vet Affairs Tennessee Valley Hlth Care Syst, Nashville, TN 37212 USA

来源：

MOLECULAR & CELLULAR ONCOLOGY | 2016年 / 3卷 / 03期

关键词：

Cancer; IBD; selenoprotein P; SEPP1; ulcerative colitis;

D O I：

10.1080/23723556.2015.1075094

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Patients with inflammatory bowel disease are often deficient in micronutrients such as selenium and have an increased risk of colon cancer. We tested whether the selenium transport protein, selenoprotein P, could modify colitis-associated cancer. Our results indicate that global SEPP1 haploinsufficiency augments tumorigenesis and mediates oxidative damage in the intestine.

引用

页数：3

共 50 条

[21] Immunohistochemical expression of p53 and oncogenes in ulcerative colitis-associated colorectal carcinoma
Brüwer, M
Schmid, KW
Senninger, N
Schürmann, G
WORLD JOURNAL OF SURGERY, 2002, 26 (03) : 390 - 396
[22] Expression analysis in colitis-associated carcinoma: a role for osteopontin?
da Silva, D. Cardoso
Sehn, M.
Elezkurtaj, S.
Kuehl, A.
Siegmund, B.
Kreis, M.
Holmer, C.
Hummel, M.
Groene, J.
Schumann, M.
JOURNAL OF CROHNS & COLITIS, 2019, 13 : S105 - S105
[23] Colonic Neuroendocrine Carcinoma in the Setting of Ulcerative Colitis and PSC: Coincidence or Colitis-Associated?
Cleveland, Noa Krugliak
Hyman, Neil
Alpert, Lindsay
Steinhagen, Emily
Rubin, David T.
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 : S818 - S819
[24] Novel plasma microRNA biomarkers for the identification of colitis-associated carcinoma
Patel, Maleene
Verma, Ajay
Aslam, Imran
Pringle, Howard
Singh, Baljit
LANCET, 2015, 385 : 78 - 78
[25] MTG16 is a tumor suppressor in colitis-associated carcinoma
McDonough, Elizabeth M.
Barrett, Caitlyn W.
Parang, Bobak
Mittal, Mukul K.
Smith, J. Joshua
Bradley, Amber M.
Choksi, Yash A.
Coburn, Lori A.
Short, Sarah P.
Thompson, Joshua J.
Zhang, Baolin
Poindexter, Shenika V.
Fischer, Melissa A.
Chen, Xi
Li, Jiang
Revetta, Frank L.
Naik, Rishi
Washington, M. Kay
Rosen, Michael J.
Hiebert, Scott W.
Wilson, Keith T.
Williams, Christopher S.
JCI INSIGHT, 2017, 2 (16)
[26] Comparison of p53 immunoexpression with allelic loss of p53 in ulcerative colitis-associated dysplasia and carcinoma
Fogt, F
Zhuang, ZP
Poremba, C
Dockhorn-Dworniczak, B
Vortmeyer, A
ONCOLOGY REPORTS, 1998, 5 (02) : 477 - 480
[27] TAMing Colitis and Colitis-Associated Colon Cancer
Bosurgi, Lidia
Uribe, Diana
Bernink, Jochem
Cuevas, Victor Delgado
Silva, Eugenio Antonio Carrera
Gagliani, Nicola
Leighton, Jonathan
Ghosh, Sourav
Rothlin, Carla
INFLAMMATORY BOWEL DISEASES, 2012, 18 : S104 - S104
[28] Ulcerative colitis-associated neoplasia
Fujii, S
Fujimori, T
Kashida, H
PATHOLOGY INTERNATIONAL, 2002, 52 (03) : 195 - 203
[29] ESD in colitis-associated dysplasia
Messmann, H.
GASTROENTEROLOGE, 2019, 14 (01): : 2 - 3
[30] TAMing Colitis and Colitis-Associated Colon Cancer
Bosurgi, Lidia
Uribe, Diana
Bernink, Jochem
Cuevas, Victor Delgado
Silva, Eugenio Antonio Carrera
Gagliani, Nicola
Leighton, Jonathan
Ghosh, Sourav
Rothlin, Carla
INFLAMMATORY BOWEL DISEASES, 2012, 18 : S13 - S14

← 1 2 3 4 5 →