T-CELL-MEDIATED CYTOTOXICITY

被引：15
|
作者：
BERKE, G
机构：
[1] The Weizmann Institute of Science, Rehovot
来源：
CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 03期
关键词：
D O I：
10.1016/0952-7915(91)90031-U
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
There are two competing theories to explain the mechanism(s) by which cytolytic T lymphocytes kill target cells: granule exocytosis of a pore-forming protein, and contact-induced internal disintegration. Accumulated evidence supports alternative pathways in lymphocytoxicity, possibly reflecting distinct effector functions expressed by different killer cells and cells at different stages of activation.
引用
收藏
页码：320 / 325
页数：6
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