BIOPROTECTIVE POTENTIAL OF BACTERIOCINS FROM SOME Lactobacillus species ISOLATED FROM FOODS

被引:0
|
作者
Oladipo, Iyabo Christianah [1 ]
Anwooko, Deborah Oluyinka [1 ]
Daramola, Dupe Ibukun [1 ]
Babalola, Funmilayo Bose [1 ]
Abidoye, Ganiyat T. [1 ]
Olawale, Olaitan Dorcas [1 ]
Iyanda, Kehinde Mary [1 ]
Ajiboye, Ouwakemi Ruth [1 ]
Osunpidan, Daniel Anuoluwapo [1 ]
Ogunremi, Aminat Theresa [1 ]
Olanbiwoninu, Afolake A. [2 ]
机构
[1] Ladoke Akintola Univ Technol, Fac Pure & Appl Sci, Dept Sci Lab Technol, Ogbomosho 210214, Oyo State, Nigeria
[2] Ajayi Crowther Univ, Fac Sci, Dept Biol Sci, Oyo, Oyo State, Nigeria
关键词
Lactobacillus species; bacteriocin; gastric tissue; total protein and globulin;
D O I
10.15414/jmbfs.2016/17.6.3.900-904
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Lactobacillus species isolated from ogi, kunnu, yoghurt and palm-wine were found to produce bacteriocins. The bacteriocins had broad spectra of antimicrobial activities against both Gram-positive and negative bacteria. The effects of the bacteriocins on Escherichia coli infections in rats were evaluated. Sprague-Dawley rats were infected with E. coli and treated with 1280 AU/ml of the bacteriocins from L. plantarum MO21, L. plantarum MP12, L. casei MK21, L. casei MO11, L. brevis MK11 and L. buchneri MY21. Escherichia coli infection caused upregulation of aspartate aminotransferase (AST), alanine aminotransferase (ALT), albumin, total protein, globulin, cholesterol, bilirubin and glucose levels in sera of the infected rats which were down-regulated in the bacteriocin treated rats. Gastric and GIT damage caused by E. coli infection were reduced in the bacteriocin-treated groups. Therefore, it is concluded that these bacteriocins may have useful biomedical applications.
引用
收藏
页码:900 / 904
页数:5
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