NECROTIZING PANCREATITIS;
NECROSECTOMY;
LOCAL LAVAGE;
D O I:
暂无
中图分类号:
R57 [消化系及腹部疾病];
学科分类号:
摘要:
In patients with severe acute pancreatitis, the most important diagnostic goal is differentiation between the interstitial-edematous and the necrotizing type of acute pancreatitis. Surgical management in patients with proven necrotizing pancreatitis is indicated in patients who develop surgical acute abdomen, sepsis, shock syndrome, multi-systemic organ failure syndrome, persistent or progressive despite maximum intensive care. The most appropriate procedure for surgical management of pancreatic necrosis is the careful removal of necrosis and preservation of vital pancreatic tissue. Necrosectomy supplemented by postoperative closed continuous lavage of the lesser sac is a procedure that offers the advantages of debridement of devitalized tissue only, and the non-surgical removal of necrotic tissue and bacterially and biologically active compounds. In comparison with a reoperation protocol, necrosectomy and continuous lavage reduce the reoperation rate as well as the need for tracheostomy. In a prospectively treated series of patients suffering from necrotizing pancreatitis, hospital mortality was 8.4% and the reoperation rate 27%. Any tissue becoming necrotic in the postoperative course of disease is rinsed with lavage fluid, thus obviating the need for repeated surgical reoperation in most patients. Local lavage is achieved by the insertion of two, in some cases five, large double-lumen tubus and the use of 8 liters (median) of lavage fluid per day.
机构:
University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Caronna R.
Benedetti M.
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机构:
Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Benedetti M.
Morelli A.
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机构:
University of Rome 'La Sapienza', Intensive Care Unit, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Morelli A.
Rocco M.
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机构:
University of Rome 'La Sapienza', Intensive Care Unit, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Rocco M.
Diana L.
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机构:
Istituto Superiore di Sanità, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Diana L.
Prezioso G.
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University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Prezioso G.
Cardi M.
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机构:
University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Cardi M.
Schiratti M.
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University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Schiratti M.
Martino G.
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机构:
Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Martino G.
Fanello G.
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Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Fanello G.
Papini F.
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机构:
Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Papini F.
Farelli F.
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机构:
Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Farelli F.
Meniconi R.L.
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Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Meniconi R.L.
Marengo M.
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机构:
Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Marengo M.
Dinatale G.
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机构:
Residency Program in General Surgery V, University of Rome 'La Sapienza', Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161
Dinatale G.
Chirletti P.
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机构:
University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161University of Rome 'La Sapienza', Department of Surgery 'Francesco Durante', General Surgery N, Rome, 00161