A CONVENIENT SYNTHESIS OF SUBSTITUTED PYRROLES FROM ESTERS OF AMINO-ACIDS

被引：14
|
作者：
KOLAR, P [1 ]
TISLER, M [1 ]
机构：
[1] UNIV LJUBLJANA,FAC NAT SCI & TECHNOL,DEPT CHEM,LJUBLJANA 61000,SLOVENIA
来源：
SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 13期
关键词：
D O I：
10.1080/00397919408010197
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new simple synthesis of substituted pyrroles from alkyl, aryl or heteroaryl substituted alpha-amino acids is described. Esters of alpha-amino acids are first reacted with dimethyl acetylenedicarboxylate and in the in situ formed enamines are thereafter cyclized in presence of sodium methoxide to pyrroles.
引用
收藏
页码：1887 / 1893
页数：7
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