ERYTHROMYCIN SYNTHESIS - A NEVER-ENDING STORY

被引：33
|
作者：
MULZER, J
机构：
[1] Institut Für Organische Chemieg, Fachbereich Chemie Der, Freien Universität, Berlin, W-1000 33
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 11期
关键词：
D O I：
10.1002/anie.199114521
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The most extensive single project in the history of organic chemistry-the total synthesis of erythromycin A and B-has received new impetus from biosynthetic studies (see related Highlight in the last edition) as well as from a new approach for the final steps of the chemical synthesis. The sequence of first lactonization, then glycosidation has been assumed incontestable; however, the reversed order of reactions recently led to considerable success. The story continues...
引用
收藏
页码：1452 / 1454
页数：3
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