SYNTHESIS OF INDOLE OXAZOLINES, POTENT 5-HT3 ANTAGONISTS

被引：9
|
作者：
SWAIN, CJ
KNEEN, C
BAKER, R
机构：
来源：
TETRAHEDRON LETTERS | 1990年 / 31卷 / 17期
关键词：
D O I：
10.1016/S0040-4039(00)97385-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of a series of indole oxazolines is reported, proceding via addition of an azabicyclic amino alcohol, in which the azacyclic nitrogen is borane protected, to an indole imidate. Selective alkylation of the indole nitrogen is facilitated by the borane protection of the highly nucleophilic azabicyclic nitrogen. © 1990.
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收藏
页码：2445 / 2448
页数：4
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