CONSTITUTIVE PROTEIN SECRETION BY GUINEA-PIG SEMINAL-VESICLE EPITHELIAL-CELLS

被引：2
|
作者：
HUDSON, DA
机构：
[1] Cell and Developmental Biology Research Unit, School of Biological Sciences, Victoria University of Wellington, Wellington
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 102卷 / 04期
关键词：
D O I：
10.1016/0305-0491(92)90066-Z
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. Secretion of pulse-labelled protein by the isolated epithelium of guinea-pig seminal vesicle epithelium was rapid, unaffected by cholinergic and adrenergic drugs, cyclic nucleotides or changes in the sodium, potassium and calcium concentrations of the "chase" medium. 2. Low temperature, NH4Cl, hyper- and hypo-osmolarity and membrane-stabilizing agents inhibited secretion which was also dependent on aerobic metabolism. 3. Monensin reduced secretion of the six labelled, relatively low molecular weight proteins recovered from the medium in a concentration-dependent, apparently non-specific manner.
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页码：701 / 706
页数：6
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