SIGNAL TRANSDUCTION AND THE FATE OF THE R7 PHOTORECEPTOR IN DROSOPHILA

被引:151
|
作者
RUBIN, GM [1 ]
机构
[1] UNIV CALIF BERKELEY,DEPT MOLEC & CELL BIOL,BERKELEY,CA 94720
关键词
D O I
10.1016/0168-9525(91)90258-R
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The sevenless protein tyrosine kinase receptor plays a central role in the pathway of cell fate induction that determines the development of the R7 photoreceptor in the Drosophila eye. In the last year we have learned much about the probable ligand for sevenless and have begun to dissect the signal transduction pathway that relays the information from the sevenless kinase. Studies of the mechanisms governing the specificity of signal transmission and reception suggest that the sevenless signal directs a bipotential cell towards a neuronal rather than a cone cell fate.
引用
收藏
页码:372 / 377
页数:6
相关论文
共 50 条
  • [1] SIGNAL-TRANSDUCTION DURING THE DEVELOPMENT OF THE DROSOPHILA R7 PHOTORECEPTOR
    SIMON, MA
    [J]. DEVELOPMENTAL BIOLOGY, 1994, 166 (02) : 431 - 442
  • [2] The role of Sevenless in Drosophila R7 photoreceptor specification
    Tomlinson, Andrew
    Mavromatakis, Yannis Emmanuel
    Arias, Ronald
    [J]. DEVELOPMENTAL BIOLOGY, 2019, 454 (02) : 181 - 189
  • [3] SENSITIVITY AND ADAPTATION IN R7, AN UV PHOTORECEPTOR, IN DROSOPHILA RETINA
    STARK, WS
    [J]. JOURNAL OF COMPARATIVE PHYSIOLOGY, 1977, 115 (01): : 47 - 59
  • [4] JUN COOPERATES WITH THE ETS DOMAIN PROTEIN POINTED TO INDUCE PHOTORECEPTOR R7 FATE IN THE DROSOPHILA EYE
    TREIER, M
    BOHMANN, D
    MLODZIK, M
    [J]. CELL, 1995, 83 (05) : 753 - 760
  • [5] SIGNALING MECHANISMS IN INDUCTION OF THE R7 PHOTORECEPTOR IN THE DEVELOPING DROSOPHILA RETINA
    YAMAMOTO, D
    [J]. BIOESSAYS, 1994, 16 (04) : 237 - 244
  • [6] Three Distinct Roles for Notch in Drosophila R7 Photoreceptor Specification
    Tomlinson, Andrew
    Mavromatakis, Yannis Emmanuel
    Struhl, Gary
    [J]. PLOS BIOLOGY, 2011, 9 (08)
  • [7] The role of the small GTPase Rap in Drosophila R7 photoreceptor specification
    Mavromatakis, Yannis Emmanuel
    Tomlinson, Andrew
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (10) : 3844 - 3849
  • [8] AN OPSIN GENE THAT IS EXPRESSED ONLY IN THE R7 PHOTORECEPTOR CELL OF DROSOPHILA
    FRYXELL, KJ
    MEYEROWITZ, EM
    [J]. EMBO JOURNAL, 1987, 6 (02): : 443 - 451
  • [9] Patterning of the R7 and R8 photoreceptor cells of Drosophila:: evidence for induced and default cell-fate specification
    Chou, WH
    Huber, A
    Bentrop, J
    Schulz, S
    Schwab, K
    Chadwell, LV
    Paulsen, R
    Britt, SG
    [J]. DEVELOPMENT, 1999, 126 (04): : 607 - 616
  • [10] Two types of Drosophila R7 photoreceptor cells are arranged randomly:: A model for stochastic cell-fate determination
    Bell, Melanie L.
    Earl, James B.
    Britt, Steven G.
    [J]. JOURNAL OF COMPARATIVE NEUROLOGY, 2007, 502 (01) : 75 - 85