MONITORING OF SERUM KL-6 ANTIGEN IN A PATIENT WITH RADIATION PNEUMONIA

被引:66
|
作者
HAMADA, H
KOHNO, N
AKIYAMA, M
HIWADA, K
机构
[1] EHIME UNIV,SCH MED,DEPT INTERNAL MED 2,SHIGENOBU,EHIME 79102,JAPAN
[2] RADIAT EFFECTS RES FDN,DEPT RADIOBIOL,HIROSHIMA,JAPAN
关键词
D O I
10.1378/chest.101.3.858
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Serum marker KL-6 antigen has been reported to be a valuable indicator of the disease activity of interstitial pneumonia. 1 It is not clear how sensitive the serum KL-6 antigen level is in reflecting histologic changes in lung tissues. We report here the results of serial measurements of serum KL-6 antigen in a 76-year-old male patient with radiation pneumonia. Serum KL-6 antigen levels were more sensitive than lactate dehydrogenase and procollagen type III N-terminal peptide. The level of serum KL-6 antigen appears to reflect the histologic changes of the lung more sensitively than does C-reactive protein.
引用
收藏
页码:858 / 860
页数:3
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