AN EXPERIMENTAL-STUDY OF THE OSTEOGENICITY OF FREE PERIOSTEAL ALLOGRAFTS WITH CYCLOSPORINE-A ADMINISTRATION

被引：2
|
作者：
HSU, M [1 ]
UMEDA, H [1 ]
NISHIJIMA, K [1 ]
机构：
[1] OKAYAMA UNIV,SCH DENT,DEPT ORAL & MAXILLOFACIAL SURG 1,OKAYAMA 700,JAPAN
来源：
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1992年 / 21卷 / 03期
关键词：
IMMUNOSUPPRESSION; PERIOSTEAL ALLOGRAFTS; CYCLOSPORINE-A; OSTEOGENIC POTENTIAL;
D O I：
10.1016/S0901-5027(05)80790-8
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Free tibial periosteum was grafted onto the dorsum (m. cutaneous trunci) of Sprague-Dawley rats to examine its osteogenic potential. The animals were divided into 3 groups based on type of: A. autogeneous periosteum, B. allogeneic periosteum and C. allogeneic periosteum, and treated with cyclosporine A immunosuppression. The osteogenic response was evaluated radiologically and histologically. This study indicates that in this model periosteal allografts with immunosuppression of the recipient result in osteogenesis. Clinical application of the technique will only be possible if immunosuppressive methods with minimal morbidity are developed so that they can be used for prolonged periods.
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页码：178 / 182
页数：5
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