The Antimicrobial Stewardship Approach to Combating Clostridium Difficile

被引:13
|
作者
Wenzler, Eric [1 ]
Mulugeta, Surafel G. [1 ]
Danziger, Larry H. [1 ,2 ]
机构
[1] Univ Illinois, Coll Pharm, Chicago, IL 60612 USA
[2] Univ Illinois, Coll Med, Chicago, IL 60612 USA
来源
ANTIBIOTICS-BASEL | 2015年 / 4卷 / 02期
关键词
antimicrobial stewardship; Clostridium difficile; restriction; diarrhea; rapid diagnostics; treatment; infection control;
D O I
10.3390/antibiotics4020198
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence and prevalence of C. difficile associate disease continues to increase both in the hospital and community setting, additional stewardship approaches are needed. This manuscript reviews stewardship interventions that have been successful against C. difficile associated disease and proposes future tactics that antimicrobial stewardship programs may employ to develop a more global approach to combat this difficult pathogen.
引用
收藏
页码:198 / 215
页数:18
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