PLATELET FUNCTION-NONPARAMETRIC TOLERANCE REGIONS IN CHILDREN AND ADOLESCENTS

被引:3
|
作者
NOWAKGOTTL, U [1 ]
BESIER, E [1 ]
KREUZ, WD [1 ]
LINDE, R [1 ]
KOERT, M [1 ]
BREDDIN, HK [1 ]
KORNHUBER, B [1 ]
机构
[1] UNIV FRANKFURT,STADTKRANKENHAUS HANAU MAIN,W-6000 FRANKFURT 1,GERMANY
来源
KLINISCHE PADIATRIE | 1992年 / 204卷 / 01期
关键词
D O I
10.1055/s-2007-1025320
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
In order to establish an univariate nonparametric pediatric tolerance region platelet function has been investigated in 105 healthy children and adolescents. In comparison to adult normal values, the bleeding time is shortened, spontaneous platelet aggregation is enhanced as well as collagen-induced platelet aggregation. 30% of the children showed an increased disaggregation in ADP-induced aggregation. A slight delay was found in the spreading of thrombocytes. Platelet volume shifted to the left. Values of beta-thromboglobulin were raised. Compared to adult values no alterations could be found in platelet shape-change. Changes of platelet functions were more apparent in the younger children.
引用
收藏
页码:37 / 42
页数:6
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