ATP-DEPENDENT PROTEASE IN HUMAN PLACENTA

被引：5
|
作者：
ISHII, A
WATABE, S
HAMADA, H
机构：
[1] ST MARIANNA MED UNIV, SCH MED, RADIOISOTOPE RES INST, KAWASAKI, KANAGAWA 213, JAPAN
[2] ST MARIANNA MED UNIV, SCH MED, DEPT OBSTET & GYNECOL, KAWASAKI, KANAGAWA 213, JAPAN
来源：
PLACENTA | 1992年 / 13卷 / 04期
关键词：
D O I：
10.1016/0143-4004(92)90058-2
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We have found that human placental mitochondria contain ATP-dependent protease in a soluble form. The molecular weight of the protease have been up to 108 000, which is the same as ATP-dependent protease in bovine adrenal cortex. Since this protease has been distributed among steroid hormone-producing tissues such as testis and adrenal cortex andATP-dependent protease can degrade cytochrome P-450scc a key enzyme in steroid hormone biosynthesis, we suggest that the protease may have an important role in the regulation ofsteroid hormone metabolism. © 1992.
引用
收藏
页码：343 / 347
页数：5
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