THENOYLTRIFLUORACETONE INDUCES LIPID-PEROXIDATION IN RAT-LIVER MITOCHONDRIA

被引:0
|
作者
GOGVADZE, V
ZHUKOVA, A
机构
关键词
MITOCHONDRIA; LIPID PEROXIDATION; THENOYLTRIFLUORACETONE;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Addition of thenoyltrifluoracetone to mitochondria oxidizing NAD-dependent substrates induced lipid peroxidation and uncoupling of oxidative phosphorylation. Butylated hydroxytoluene, an antioxidant, prevented accumulation of lipid peroxidation products but failed to prevent deenergization of the mitochondria.
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页码:303 / 308
页数:6
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