THENOYLTRIFLUORACETONE INDUCES LIPID-PEROXIDATION IN RAT-LIVER MITOCHONDRIA

被引：0
|
作者：
GOGVADZE, V
ZHUKOVA, A
机构：
来源：
GENERAL PHYSIOLOGY AND BIOPHYSICS | 1993年 / 12卷 / 03期
关键词：
MITOCHONDRIA; LIPID PEROXIDATION; THENOYLTRIFLUORACETONE;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Addition of thenoyltrifluoracetone to mitochondria oxidizing NAD-dependent substrates induced lipid peroxidation and uncoupling of oxidative phosphorylation. Butylated hydroxytoluene, an antioxidant, prevented accumulation of lipid peroxidation products but failed to prevent deenergization of the mitochondria.
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页码：303 / 308
页数：6
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