THE FORMATION OF UNSATURATED DITERPENOID ALCOHOLS FROM 1,4-GLYCOLS WITH N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL

被引：2
|
作者：
DAVIS, CA [1 ]
GUILLERMOALVAREZ, R [1 ]
HANSON, JR [1 ]
HITCHCOCK, PB [1 ]
机构：
[1] UNIV SUSSEX,SCH MOLEC SCI,BRIGHTON BN1 9QJ,E SUSSEX,ENGLAND
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 06期
关键词：
D O I：
10.1039/p19900001619
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Treatment of the 1,4-diol ent-6β,19-dihydroxykaur-16-ene with DMFDMA, quaternization of the resultant formamido-acetal with methyl iodide, followed by elimination and hydrolysis of the resultant formate gives the ent-19-hydroxykaur-5,16- and -6,16-dienes. Labelling studies show that the reaction proceeds with the elimination of a hydrogen atom that is trans to the axial C-6 alcohol.
引用
收藏
页码：1619 / 1622
页数：4
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