SYNTHESIS OF SUBSTITUTED NICOTINAMIDES FROM ENAMINES DERIVED FROM N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL

被引：0
|
作者：
ABUSHANAB, FA
ALY, FM
WAKEFIELD, BJ
机构：
[1] UNIV SALFORD,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCS,ENGLAND
[2] AL-AZHAR UNIV,FAC SCI,DEPT CHEM,CAIRO,EGYPT
来源：
SYNTHESIS-STUTTGART | 1995年 / 08期
关键词：
1,2-DIHYDRO-2-OXOPYRIDINE-3-CARBOXAMIDES 1,2-DIHYDRO-2-THIOXOPYRIDINE-3-CARBOXAMIDES; MALONAMIDE; CYANOTHIOACETAMIDE; CYANOACETAMIDE;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reactions of 1,3-dicarbonyl compounds with N,N-dimethylformamide dimethyl acetal followed by malonamide in the presence of sodium hydride give 5,6-disubstituted 1,2-dihydro-2-oxopyridine-3-carboxamides 3 a-c, whereas reactions of the intermediate enamines with cyanothioacetamide or cyanoacetamide in the presence of piperidine give 4,5-disubstituted 1,2-dihydro-2-thioxopyridine-3-carboxamides 6 a-c and 1,2-dihydro-2-oxopyridine-3-carboxamides 6 d-b.
引用
收藏
页码：923 / 925
页数：3
相关论文
共 50 条
  • [1] SYNTHESIS OF 2,3,5,6-TETRASUBSTITUTED PYRIDINES FROM ENAMINES DERIVED FROM N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL
    ABUSHANAB, FA
    REDHOUSE, AD
    THOMPSON, JR
    WAKEFIELD, BJ
    [J]. SYNTHESIS-STUTTGART, 1995, (05): : 557 - 560
  • [2] N,N-Dimethylformamide dimethyl acetal
    Kidjemet, D
    [J]. SYNLETT, 2002, (10) : 1741 - 1742
  • [3] N,N-Dimethylformamide dimethyl acetal (DMFDMA): from derivatisation to C1 synthon
    Araujo, Natalie Ferreira
    Ferreira, Sabrina Baptista
    [J]. AUSTRALIAN JOURNAL OF CHEMISTRY, 2024, 77 (06)
  • [4] REACTION OF N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL WITH AMINO-SUGARS
    STEFANSKA, B
    FALKOWSKI, L
    [J]. POLISH JOURNAL OF CHEMISTRY, 1982, 56 (4-6) : 855 - 857
  • [5] NAPHTHALENES AND BIPHENYLS VIA A NOVEL REACTION OF N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL
    ABDULLA, RF
    FUHR, KH
    GAJEWSKI, RP
    SUHR, RG
    TAYLOR, HM
    UNGER, PL
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1980, 45 (09): : 1724 - 1725
  • [6] THE FORMATION OF UNSATURATED DITERPENOID ALCOHOLS FROM 1,4-GLYCOLS WITH N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL
    DAVIS, CA
    GUILLERMOALVAREZ, R
    HANSON, JR
    HITCHCOCK, PB
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1990, (06): : 1619 - 1622
  • [7] CONVENIENT CYCLIZATION OF ORTHO-DIFUNCTIONAL HETEROCYCLES WITH N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL
    STANOVNI.B
    TISLER, M
    [J]. SYNTHESIS-STUTTGART, 1974, (02): : 120 - 122
  • [8] Corticosteroid derivatization: Unexpected results obtained using N,N-dimethylformamide dimethyl acetal on dexamethasone.
    Negriolli, J
    Maume, D
    Deniaud, D
    Andre, F
    [J]. TETRAHEDRON LETTERS, 1996, 37 (30) : 5365 - 5366
  • [9] Catalytic Synthesis of N, N-Dimethylformamide from Carbon Dioxide and Dimethylamine
    Wu, Yajuan
    Luo, Jingwen
    Huang, Yongji
    [J]. PROGRESS IN CHEMISTRY, 2022, 34 (06) : 1431 - 1439
  • [10] ELECTRODEPOSITION OF NICKEL FROM N,N-DIMETHYLFORMAMIDE
    SRIVASTAVA, HK
    TIKOO, PK
    [J]. SURFACE & COATINGS TECHNOLOGY, 1987, 31 (04): : 343 - 349
12345