NEW SYNTHESIS OF SUGAR, NUCLEOSIDE AND ALPHA-AMINO-ACID PHOSPHONATES

被引：36
|
作者：
BARTON, DHR
GERO, SD
QUICLETSIRE, B
SAMADI, M
机构：
[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE
[2] TEXAS A&M UNIV SYST,DEPT CHEM,COLLEGE STN,TX 77843
来源：
TETRAHEDRON | 1992年 / 48卷 / 09期
关键词：
PHOSPHONATES-THIOHYDROXAMIC ESTERS-RADICAL-DECARBOXYLATION-AZT;
D O I：
10.1016/S0040-4020(01)88721-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Photolysis of N-hydroxy-2-thiopyridone esters derived from uronic acids or alpha-amino acids in presence of vinyl phosphonate affords the corresponding phosphonate derivatives. A convenient route for the synthesis of the isostere of AZT-5' monophosphate is described.
引用
收藏
页码：1627 / 1636
页数：10
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