Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

被引：11
|
作者：
Abdel-Sattar, Essam [1 ]
Abou-Hussein, Dina [1 ,2 ]
Petereit, Frank [3 ]
机构：
[1] Cairo Univ, Fac Pharm, Dept Pharmacognosy, Cairo 11562, Egypt
[2] King Abdulaziz Univ, Fac Pharm, Dept Nat Prod & Alternat Med, Jeddah 21589, Saudi Arabia
[3] Univ Munster, Inst Pharmaceut Biol & Phytochemistry, D-48149 Munster, Germany
来源：
PHARMACOGNOSY RESEARCH | 2015年 / 7卷 / 01期
关键词：
Cervical adenocarcinoma; euphol; Euphorbia ammak;
D O I：
10.4103/0974-8490.147136
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), a-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.
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收藏
页码：14 / 17
页数：4
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