A STEREOCONTROLLED SYNTHESIS OF HYDROXYETHYLENE DIPEPTIDE ISOSTERES USING NOVEL, CHIRAL AMINOALKYL EPOXIDES AND GAMMA-(AMINOALKYL) GAMMA-LACTONES

被引：153

|

作者：

EVANS, BE ^{[1
]}

RITTLE, KE ^{[1
]}

HOMNICK, CF ^{[1
]}

SPRINGER, JP ^{[1
]}

HIRSHFIELD, J ^{[1
]}

VEBER, DF ^{[1
]}

机构：

[1] MERCK INST THERAPEUT RES,RAHWAY,NJ 07065

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1985年 / 50卷 / 23期

关键词：

D O I：

10.1021/jo00223a037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

收藏

页码：4615 / 4625

页数：11

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[42] SYNTHESIS OF BOTH ENANTIOMERS OF OPTICALLY PURE SATURATED AND ALPHA,BETA-UNSATURATED GAMMA-SUBSTITUTED GAMMA-LACTONES FROM CHIRAL SULFOXIDES - X-RAY MOLECULAR-STRUCTURE OF (3R,4S)-4-METHYL-4-TERT-BUTYL-3-(PARA-TOLYLTHIO)BUTANOLIDE AND OF (3R,4R)-4-(CYCLOHEX-1-ENYL)-4-METHYL-3-(PARA-TOLYLTHIO)BUTANOLIDEL
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GANAZZOLI, F
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JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1986, (08): : 1405 - 1415

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