P-31-MAGNETIC RESONANCE SPECTROSCOPY IN MIGRAINE WITHOUT AURA

被引:120
|
作者
MONTAGNA, P
CORTELLI, P
MONARI, L
PIERANGELI, G
PARCHI, P
LODI, R
IOTTI, S
FRASSINETI, C
ZANIOL, P
LUGARESI, E
BARBIROLI, B
机构
[1] UNIV BOLOGNA,INST NEUROL,BOLOGNA,ITALY
[2] UNIV BOLOGNA,MED PATHOL INST D CAMPANACCI,DEPT CLIN BIOCHEM,BOLOGNA,ITALY
[3] UNIV MODENA,INST BIOCHEM,I-41100 MODENA,ITALY
[4] UNIV MODENA,DEPT RADIOL,I-41100 MODENA,ITALY
关键词
D O I
10.1212/WNL.44.4.666
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We investigated 22 patients with migraine without aura, all drug-free and in headache-free periods, by means of P-31-magnetic resonance spectroscopy (MRS) of brain and muscle. Brain P-31-MRS showed significantly low phosphocreatine, increased adenosine diphosphate, and decreased phosphorylation potential. There was a slow rate of phosphocreatine recovery after exercise in the muscle of 12 of 22 patients. Energy metabolism is abnormal in migraine without aura, as previously demonstrated in patients with migraine stroke and migraine with aura.
引用
收藏
页码:666 / 669
页数:4
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