PERFUSION QUANTITATION USING POSITRON EMISSION TOMOGRAPHY

被引:8
|
作者
HOFFMAN, JM
COLEMAN, RE [1 ]
机构
[1] DUKE UNIV, MED CTR, DEPT RADIOL, NUCL MED SECT, BOX 3949, DURHAM, NC 27710 USA
[2] DUKE UNIV, MED CTR, DEPT MED, DIV NEUROL, DURHAM, NC 27710 USA
关键词
CEREBRAL BLOOD FLOW; POSITRON EMISSION TOMOGRAPHY; PERFUSION;
D O I
10.1097/00004424-199212002-00005
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Positron emission tomography (PET) is assuming increasing importance as a clinical and investigative functional imaging modality. Cerebral blood flow determination with PET is now more easily performed due to improvement in tomograph design, increased speed and ease of data analysis, and improvement in radiopharmaceutical synthesis and delivery. This article reviews the historic development of the PET, the evolution of cerebral blood flow measurement techniques with PET, technical considerations in PET imaging, radio-pharmaceuticals for cerebral blood flow determination, and tracer kinetic models used for cerebral blood flow determination. Representative examples of PET cerebral blood now imaging are shown and the evolving applications to brain mapping are discussed.
引用
收藏
页码:S22 / S26
页数:5
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