SHORT-TERM USE OF AMOXICILLIN-CLAVULANATE DURING UPPER RESPIRATORY-TRACT INFECTION FOR PREVENTION OF ACUTE OTITIS-MEDIA

被引：46

作者：

HEIKKINEN, T

RUUSKANEN, O

ZIEGLER, T

WARIS, M

PUHAKKA, H

机构：

[1] UNIV TURKU, DEPT PEDIAT, TURKU, FINLAND

[2] UNIV TURKU, DEPT VIROL, TURKU, FINLAND

[3] UNIV TURKU, DEPT OTOLARYNGOL, TURKU, FINLAND

[4] UNIV TAMPERE, DEPT OTOLARYNGOL, TAMPERE, FINLAND

来源：

JOURNAL OF PEDIATRICS | 1995年 / 126卷 / 02期

基金：

芬兰科学院;

关键词：

D O I：

10.1016/S0022-3476(95)70569-4

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We performed a randomized, double-blind, placebo-controlled study to determine whether acute otitis media could be prevented by antibiotic therapy initiated promptly after the appearance of symptoms of upper respiratory tract infection, One hundred four children aged 1 to 4 years received a 7-day course of either amoxicillin-clavulanate or placebo, Acute otitis media developed in 9 (18%) of the 50 children receiving amoxicillin clavulanate and in 12 (22%) of the 54 children receiving placebo (p = 0.59).

引用

页码：313 / 316

页数：4

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