Superior orbital fissure syndrome and its mimics: What the radiologist should know?

Aim of this study: The aim of this study was to assess the rule of imaging in the superior orbital fissure syndrome (SOFS) and to identify the rule of the radiologist in guidance of the management. Material and methods: This study was conducted on 7 patients with clinical diagnosis of SOFS. Contrast enhanced MRI was used in examination of all patients. With exception of metastatic lesions, follow up MRI study was performed to all lesions. Final diagnosis was reached either by dramatic response to cortico-steroid therapy, tissue biopsy or by correlation with clinical and other imaging data. Results: In all patients enhancing abnormal T1 and T2 intermediate intensities are seen localized to the anatomical site of the superior orbital fissure (SOF). Four patients presented with sheet like enhancement casting the SOF. Nodular enhancement is noted along the medial aspect of the SOF in one case. Two patients presented with sizable destructive space occupying lesions at SOF. Conclusion: In management of SOFS, if there is a dramatic clinical and radiological response to corticosteroid therapy, we recommend MRI follow-up study after 6 week interval. As the symptoms were resolving, the potential risks associated with tissue biopsy from that area will be unacceptable. (C) 2012 Egyptian Society of Radiology and Nuclear Medicine. Production and hosting by Elsevier B.V. Open access under CC BY-NC-ND license.