UNUSUAL FORMATION OF A NOVEL PYRROLO[1',2'/1,2]PYRIDO[3,4-B]INDOLE

被引：2

作者：

GIRI, VS ^{[1
]}

DAS, SK ^{[1
]}

SANKAR, PJ ^{[1
]}

SHOOLERY, JN ^{[1
]}

KEIFER, P ^{[1
]}

机构：

[1] VARIAN ASSOCIATES INC,PALO ALTO,CA 94303

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 04期

关键词：

D O I：

10.1002/jhet.5570290415

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 1-methyl-3,4-dihydro-,beta-carboline 1 with methyl glycidate 4 gave the novel tetracyclic conjugated gamma-lactam, 2-methylpyrrolo[l',2':1,2]pyrido[3,4-b]indol-3-one 5. The same compound 5 was obtained in higher yield when 1 was treated with methyl 2-methoxyacrylate 7. Sodium borohydride treatment of 5 resulted in the cleavage of lactam to yield the unexpected alcohols 8 and 9.

引用

页码：767 / 769

页数：3

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